The Inhibitory Effect of IFN-g on Protease HTRA1 Expression in Rheumatoid Arthritis
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Print ISSN: 0022-1767 Online ISSN: 1550-6606. Immunologists, Inc. All rights reserved. Copyright © 2014 by The American Association of 9650 Rockville Pike, Bethesda, MD 20814-3994. The American Association of Immunologists, Inc., is published twice each month by The Journal of Immunology at L iter H ill L irary of he H ealth Scnces/ U .A .B . on A uust 6, 2014 hp://w w w jim m unl.org/ D ow nladed from
منابع مشابه
The inhibitory effect of IFN-γ on protease HTRA1 expression in rheumatoid arthritis.
The high temperature requirement A1 (HTRA1) is a potent protease involved in many diseases, including rheumatoid arthritis (RA). However, the regulatory mechanisms that control HTRA1 expression need to be determined. In this study, we demonstrated that IFN-γ significantly inhibited the basal and LPS-induced HTRA1 expression in fibroblasts and macrophages, which are two major cells for HTRA1 pro...
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